The Path to a Long and Healthy Life: NAD

As specialists in Physical Medicine and Rehabilitation, we focus not only on treating existing conditions but also on sustainable ways to maintain a healthy and long life. In recent years, one molecule that has attracted increasing attention in the scientific community is NAD (Nicotinamide Adenine Dinucleotide). This coenzyme, which plays a critical role in our cells’ energy production, has a decisive impact on the aging process and chronic health issues.

The Power of Mitochondria and NAD

Known as the powerhouses of our cells, mitochondria produce the energy that allows us to move, think, and even breathe in our daily lives. At the center of this process lies NAD. NAD enables the energy obtained from nutrients to be transformed into a usable form at the cellular level. Without sufficient NAD, mitochondria cannot function efficiently.

NAD Deficiency and Chronic Fatigue

Stress, poor sleep, unhealthy diets, and environmental toxins brought on by modern life can lead to a decline in NAD levels. NAD deficiency most commonly manifests as chronic fatigue, low energy, difficulties with concentration, and a general decrease in quality of life. Especially in middle age and beyond, NAD levels naturally decline, which is an important factor explaining the fatigue, muscle weakness, and slower recovery processes associated with aging.

NAD for Healthy Living and Longevity

Scientific studies show that supporting NAD levels not only meets our daily energy needs but may also have a positive effect on longevity. NAD supports many vital functions, from DNA repair to the regulation of the immune system. Higher NAD levels make cells more resilient, strengthen the body’s ability to fight oxidative stress, and promote a more balanced metabolism.

Ways to Support NAD Levels

• Regular exercise: Improves mitochondrial function and supports NAD metabolism.
• Healthy nutrition: A diet rich in B vitamins facilitates NAD production.
• Quality sleep: Strengthens cellular repair processes.
• NAD precursors (such as nicotinamide riboside or nicotinamide mononucleotide supplements): Among the most studied methods in recent years.

Conclusion

NAD emerges not only as a key player in energy production but also as a cornerstone of healthy living and longevity. Preserving our NAD levels is essential for protecting against chronic fatigue and continuing life with a more vibrant body and mind. As physicians working in the field of physical medicine and rehabilitation, we believe that understanding and supporting this biological mechanism is a powerful step toward improving our patients’ quality of life.

Dr. Elif Berber
Assistant Professor, Specialist in Physical Medicine and Rehabilitation